Journal of Dynamics in Agricultural Research
Available online at http://www.journaldynamics.org/djpam
Vol.2(1), pp.1-5, May 2017
Article ID: DJPAM/JDYA75013619
Copyright © 2017
Original Research Paper
Epidemiology of Staphylococcus aureus, as a cause of wound infections in Ondo State and its Antibiogram
Department of Microbiology, Adekunle Ajasin University, Akungba-Akoko, Ondo State, Nigeria.
*Corresponding Author. E-mail:firstname.lastname@example.org.
Received 8 February, 2017; Accepted 13 April, 2017; Available on-line 28 April, 2017.
Background: Epidemiology of Staphylococcus aureus, as a cause of wound infections in Ondo State and its antibiogram was investigated in this study. The organism is gram-positive cocci arranged in irregular, grape like clusters; they are normally present on human and animal skin where most of them live as commensal. This study is therefore designed to investigate the rate of occurrence of S. aureus among the traumatic patients and the antibiotics that can be adequate for the treatment of the disease it caused.
Methods: Swab samples were collected from patients attending primary, secondary and tertiary health care centers in the State. Two hundred samples were collected and brought to Adekunle Ajasin University`s Microbiology Laboratory and subjected to standard microbiological analysis for the identification of the pathogen. Sensitivity of the organism to commercially available antibiotics was done after the organism was prepared for pure culture using agar diffusion technique. For the study data, one way ANOVA was done using statistical software SPSS Version 20.
Results: A 50% rate of infection with S. aureus was detected from this study out of 200 samples examined, and the organism was more frequent in males 60 (30%) than females 40 (20%). Concerning the lesions from which samples were collected, the following percentages of S.aureus were isolated from each of the lesion: trauma 20 (50%), burns 16 (40%), abscesses 18 (45%), boils 22 (55%) and wounds 24 (60%), respectively. Moreover, the organism was sensitive to the test antibiotics in a descending order as follows: gentamycin (78%), streptomycin (32%), ceporex (18%), tarivid (17%), peflacine (17%), ciprofloxacin (17%), augmentin (6%), nalidixic acid (3.5%), ampicillin (3.5%) and septrin (0%).
Conclusion: This study showed that 50% of wound infections in Ondo State were caused by S. aureus and that the organism displayed multiple resistances to all the antibiotics except gentamycin which mediated 78% effectiveness against the organism. However, in case of an outbreak, gentamycin can be used for treating infection caused by the pathogen. It is therefore suggested that effort should be reinforced at coming up with control strategy to prevent the infection from attaining epidemiological status.
Keywords: Epidemiology, Staphylococcus aureus, antibiogram.